"They lived by the fundamental precept that leaving unrealized potential on the table letting something remain only good, when it can become great is a secular sin".
Jim Collins The author from Good to Great - Business Week
Drug discovery- AEBI
AEBi is a development-stage biopharmaceutical company engaged in the discovery and development of therapeutic peptides. AEBi has developed “SoAP”, a combinatorial biology screening platform technology.
Using SoAP, AEBi can develop drugs to many illnesses. This technology will significantly accelerate the drug discovery R&D phase and reduce attrition rate of new drug candidates.
The advantage of the technology is that it generates very specific lead compounds with a great functionality, and improved pharmacological properties. Such lead compounds should give very effective drugs, with the smallest side effects.
In 2010n AEBi has been involved in two cancer projects. The leading one was using Epidermal Growth Factor Receptor (EGFR) as a target. AEBI have found many leads that were proven to be functionally positive.
The second project AEBI is involved in uses Insulin like Growth Factor Receptor (IGFR) as a target. The company already got positive clones, and is in the process of isolating more hits.
Regarding Peptides short life cycle: AEBi decided to choose a generic strategy to substantially increase our peptides half lives in blood. The chosen method was to attach the peptides to a Polyethylene glycol (PEG) molecule.
Aviation
Urban Aeronautics Ltd - is developing a family of Vertical-Takeoff-and-Landing (VTOL), utility aircraft with internal (ducted fan) lift rotors. These aircraft, known as ‘Fancraft’™, are capable of safely carrying out a vast range of groundbreaking missions in confined areas. Fancraft™ are designed to in accordance with current Federal Aviation Administration (FAA) certification standards
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